PQC: Yes, technologically we have made a lot of breakthroughs. But unfortunately, more than half of those breakthroughs has been dedicated to war, police state, and destruction of human life, human rights and liberty. That itself is a very devolution of humanity. Big corporations such as Monsanto, Pfizer, Bayer have colluded with Governments in weaponizing foods and medicines against the people! You just cannot make this up! All have been exposed with ample proofs. And what have “we the people” reacted to these findings and exposures ? “Oh… uhm it’s conspiracy theory”!
Today “we the people” have been trained-mind controlled to be indifferent to their fellow human beings suffering. The indifference exists not only just between “nations”, between “races” in accordance with nationalism, patriotism, but also within a society, a community, a neighborhood . So meaningful for patriotism huh!
Looking in the eyes of each other is no longer a normal interaction between people even among one’s own neighborhood . What has happened to all of us? Why? How has it come about? Well, just look at ourselves in the mirror and we will have the answer. We all deserve it. We all are complicit in this process of devolution of ourselves as human beings. We all tolerate it, let it happens, and participate in it because we believe in Authority, in Government, in absurd, stupid patriotism with an imagined reverence of the State.
Don’t Just Give Thanks. Pay It Forward One Act of Kindness at a Time
By John W. Whitehead
“As we express our gratitude, we must never forget that the highest appreciation is not to utter words, but to live by them.” – John F. Kennedy
November 21, 2017
– It’s been a hard, heart-wrenching, stomach-churning kind of year filled with violence and ill will.
It’s been a year of hotheads and blowhards and killing sprees and bloodshed and take downs.
It’s been a year in which tyranny took a step forward and freedom got knocked down a few notches.
It’s been a year with an abundance of bad news and a shortage of good news.
It’s been a year of too much hate and too little kindness.
Now we find ourselves approaching that time of year when, as George Washington and Abraham Lincoln proclaimed, we’re supposed to give thanks as a nation and as individuals for our safety and our freedoms.
It’s not an easy undertaking.
How do you give thanks for freedoms that are constantly being eroded? How do you express gratitude for one’s safety when the perils posed by the American police state grow more treacherous by the day? How do you come together as a nation in thanksgiving when the powers-that-be continue to polarize and divide us into warring factions?
It’s not going to happen overnight. Or with one turkey dinner. Or with one day of thanksgiving.
Thinking good thoughts, being grateful, counting your blessings and adopting a glass-half-full mindset are fine and good, but don’t stop there.
This world requires doers, men and women (and children) who will put those good thoughts into action.
It says a lot (and nothing good) about the state of our world and the meanness that seems to have taken center stage that we now have a day (World Kindness Day) devoted to making the world more collectively human in thoughts and actions. The idea for the day started after a college president in Japan was mugged in a public place and nobody helped him.
Unfortunately, you hear about these kinds of incidents too often.
A 15-year-old girl was gang raped in a schoolyard during a homecoming dance. As many as 20 people witnessed the assault over the course of two and a half hours. No one intervened to stop it.
A 28-year-old woman was stabbed, raped and murdered outside her apartment early in the morning. Thirty-eight bystanders witnessed the attack and failed to intervene. The woman, Kitty Genovese, died from her wounds at the locked doorway to her apartment building.
A 58-year-old man waded into chest-deep water in the San Francisco Bay in an apparent suicide attempt. For an hour, Raymond Zack stood in the shallow water while 75 onlookers watched. Police and firefighters were called in but failed to intervene, citing budget cuts, a lack of training in water rescue, fear for their safety and a lack of proper equipment. The man eventually passed out and later died of hypothermia. Eventually, an onlooker volunteered to bring the body back to the beach.
A homeless man intervened to save a woman from a knife-wielding attacker. He saved the woman but was stabbed repeatedly in the process. As The Guardian reports, “For more than an hour he lay dying in a pool of his own blood as dozens walked by. Some paused to stare, others leaned in close. One even shook his body and then left, while someone else recorded a video of the entire proceeding.”
This is how evil prevails: when good men and women do nothing.
By doing nothing, the onlookers become as guilty as the perpetrator.
“If I were to remain silent, I’d be guilty of complicity,” declared Albert Einstein.
It works the same whether you’re talking about kids watching bullies torment a fellow student on a playground, bystanders watching someone dying on a sidewalk, or citizens remaining silent in the face of government atrocities.
There’s a term for this phenomenon where people stand by, watch and do nothing—even when there is no risk to their safety—while some horrific act takes place (someone is mugged or raped or bullied or left to die): it’s called the bystander effect.
Psychological researchers John Darley and Bibb Latane mounted a series of experiments to discover why people respond with apathy or indifference instead of intervening.
Their findings speak volumes about the state of our nation and why “we the people” continue to suffer such blatant abuses by the police state.
According to Darley and Latane, there are two critical factors that contribute to this moral lassitude.
First, there’s the problem of pluralistic ignorance in which individuals in a group look to others to determine how to respond. As Melissa Burkley explains in Psychology Today, “Pluralistic ignorance describes a situation where a majority of group members privately believe one thing, but assume (incorrectly) that most others believe the opposite.”
Second, there’s the problem of “diffusion of responsibility,” which is compounded by pluralistic ignorance. Basically, this means that the more people who witness a catastrophic event, the less likely any one person will do anything because each thinks someone else will take responsibility. In other words, no one acts to intervene or help because each person is waiting for someone else to do so.
Now the temptation is to label the bystanders as terrible people, monsters even.
Yet as Mahzarin Banaji, professor of psychology at Harvard University points out, “These are not monsters. These are us. This is all of us. This is not about a few monsters. This is about everybody. It says something very difficult to us. It says that perhaps had we been standing there, we ourselves, if we were not better educated about this particular effect and what it does to us, we may fall prey to it ourselves.”
Historically, this bystander syndrome in which people remain silent and disengaged—mere onlookers—in the face of abject horrors and injustice has resulted in whole populations being conditioned to tolerate unspoken cruelty toward their fellow human beings: the crucifixion and slaughter of innocents by the Romans, the torture of the Inquisition, the atrocities of the Nazis, the butchery of the Fascists, the bloodshed by the Communists, and the cold-blooded war machines run by the military industrial complex.
So what can you do about this bystander effect?
Be a hero, suggests psychologist Philip Zimbardo.
“Each of us has an inner hero we can draw upon in an emergency,” Zimbardo concluded. “If you think there is even a possibility that someone needs help, act on it. You may save a life. You are the modern version of the Good Samaritan that makes the world a better place for all of us.”
Zimbardo is the psychologist who carried out the Stanford Prison Experiment which studied the impact of perceived power and authority on middle class students who were assigned to act as prisoners and prison guards. The experiment revealed that power does indeed corrupt (the appointed guards became increasingly abusive), and those who were relegated to being prisoners acted increasingly “submissive and depersonalized, taking the abuse and saying little in protest.”
What is the antidote to group think and the bystander effect?
Be an individual. Listen to your inner voice. Take responsibility.
“If you find yourself in an ambiguous situation, resist the urge to look to others and go with your gut instinct,” says Burkley. “If you think there is even a possibility that someone is in need, act on it. At worst, you will embarrass yourself for a few minutes, but at best, you will save a life.”
“Even if people recognize that they are witnessing a crime, they may still fail to intervene if they do not take personal responsibility for helping the victim,” writes Burkley. “The problem is that the more bystanders there are, the less responsible each individual feels.”
In other words, recognize injustice. Don’t turn away from suffering.
Refuse to remain silent. Take a stand. Speak up. Speak out.
This is what Zimbardo refers to as “the power of one.” All it takes is one person breaking away from the fold to change the dynamics of a situation. “Once any one helps, then in seconds others will join in because a new social norm emerges: Do Something Helpful.”
“I swore never to be silent whenever and wherever human beings endure suffering and humiliation,” stated Holocaust Elie Wiesel in his Nobel Peace Prize acceptance speech in 1986. “We must always take sides. Neutrality helps the oppressor, never the victim. Silence encourages the tormentor, never the tormented. Sometimes we must interfere. When human lives are endangered, when human dignity is in jeopardy, national borders and sensitivities become irrelevant. Wherever men or women are persecuted because of their race, religion, or political views, that place must – at that moment – become the center of the universe.”
Unfortunately, as I make clear in my book Battlefield America: The War on the American People, too many Americans have opted to remain silent when it really matters while instead taking a stand over politics rather than human suffering.
That needs to change.
I don’t believe we’re inherently monsters. We just need to be more conscientious and engaged and helpful.
The Good Samaritans of this world don’t always get recognized, but they’re doing their part to push back against the darkness.
For instance, earlier this year in Florida, a family of six—four adults and two young boys—were swept out to sea by a powerful rip current in Panama City Beach. There was no lifeguard on duty. The police were standing by, waiting for a rescue boat. And the few people who had tried to help ended up stranded, as well.
Those on shore grouped together and formed a human chain. What started with five volunteers grew to 15, then 80 people, some of whom couldn’t swim.
One by one, they linked hands and stretched as far as their chain would go. The strongest of the volunteers swam out beyond the chain and began passing the stranded victims of the rip current down the chain.
One by one, they rescued those in trouble and pulled each other in.
There’s a moral here for what needs to happen in this country if we only can band together and prevail against the riptides that threaten to overwhelm us.
Here’s what I suggest.
Instead of just giving thanks this holiday season with words that are too soon forgotten, why not put your gratitude into action with deeds that spread a little kindness, lighten someone’s burden, and brighten some dark corner?
I’m not just talking about volunteering at a soup kitchen or making a donation to a charity that does good work, although those are fine things, too.
What I’m suggesting is something that everyone can do no matter how tight our budgets or how crowded our schedules.
Pay your blessings forward.
Engage in acts of kindness. Smile more. Fight less.
Focus on the things that unite instead of that which divides. Be a hero, whether or not anyone ever notices.
Do your part to push back against the meanness of our culture with conscious compassion and humanity. Moods are contagious, the good and the bad. They can be passed from person to person. So can the actions associated with those moods, the good and the bad.
Even holding the door for someone or giving up your seat on a crowded train are acts of benevolence that, magnified by other such acts, can spark a movement.
Imagine a world in which we all lived in peace.
John Lennon tried to imagine such a world in which there was nothing to kill or die for, no greed or hunger. He was a beautiful dreamer whose life ended with an assassin’s bullet on December 8, 1980.
Still, that doesn’t mean the dream has to die, too.
There’s something to be said for working to make that dream a reality. As Lennon reminded his listeners, “War is over, if you want it.”
The choice is ours, if we want it.
Constitutional attorney and author John W. Whitehead is founder and president of The Rutherford Institute. His new book Battlefield America: The War on the American People (SelectBooks, 2015) is available online at http://www.amazon.com. Whitehead can be contacted at firstname.lastname@example.org.
Big Pharma and Medical Device Manufacturers
Big Pharma is the nickname given to the world’s vast and influential pharmaceutical industry and its trade group, the Pharmaceutical Research and Manufacturers of America or PhRMA. Big Pharma and medical device companies make billions of dollars every year selling drugs and devices — including those that were recalled or involved in fraud or product liability lawsuits.
The pharmaceutical industry — nicknamed Big Pharma — is one of the most powerful industries in the world. The global revenue for pharmaceuticals was over $1 trillion in 2014. But nowhere else in the world do the drug and medical device industries have as much power and make as much money as in the U.S.
In fact, Americans spent an all-time high of $457 billion on prescription drugs in 2015. By 2020, it will be $610 billion. Medical devices are also lucrative. The U.S. makes up about half of the world’s share of the market at about $148 billion, according to the U.S. Department of Commerce.
Meanwhile, drug prices continue to rise. Consulting firm Segal Consulting expects drug prices for Americans under age 65 to rise 11.6 percent in 2017. In contrast, wages are only expected to rise 2.5 percent, leaving many American unable to afford their medications.
Big Pharma even contributes heavily to the annual budget of the U.S. Food and Drug Administration (FDA) through application fees (user fees) for its new products. Experts say the industry contributes about two thirds of the FDA’s budget.
Five of the top 10 pharma and medical device companies for 2016 are headquartered in the U.S.: Johnson & Johnson, Pfizer, Merck, Gilead and AbbVie.
The underside of the industry reveals a history of fraud, bribery, product liability lawsuits and scandals that led to billions in settlements — a known cost of doing business for these companies who are “too big to jail.” Despite criminal charges and fines, the companies continue to do business.
Who is Big Pharma?
The majority of drugs and medical devices have ties to a small group of parent companies. Prescription drugs and devices manufactured by these companies bring in billions in profits. The biggest drug makers may also have subsidiaries that manufacture medical devices.
Pharmaceutical companies are typically larger and make more money than companies that focus on medical devices.
The most powerful drug and device companies are members of the Pharmaceutical Research and Manufacturers of America (PhRMA) — the industry’s U.S. lobbying organization.
With the help of staggering profits and an army of 1,378 paid lobbyists, the industry spreads its influence on Capitol Hill. From 1998 to 2016, Big Pharma spent nearly $3.5 billion on lobbying expenses — more than any other industry. In 2016 alone, it spent about $246 million — more than the defense industries and corporate business lobbyists combined.
Only 28 percent of Americans have a good opinion of Big Pharma. In fact, they are the second most hated industry in the U.S. They are also the biggest defrauder of the Federal Government under the False Claims Act, according to consumer watchdog group Public Citizen.
The Reputation Institute evaluated public perception of 17 pharmaceutical companies for products and services, innovation, workplace, governance, citizenship and financial performance. The Institute based its results on 16,800 ratings from the U.S., U.K., Canada and other countries.
Of all the countries, the U.S. had the lowest opinion of pharmaceutical companies. Older people had the most favorable view of the industry.
2016 Top 10 Pharmaceutical Companies by Sales:
|Johnson & Johnson||$71.89 billion||$70.04 billion|
|Pfizer||$52.82 billion||$48.85 billion|
|Roche||$50.11 billion||$47.70 billion|
|Novartis||$48.52 billion||$49.41 billion|
|Merck & Co.||$39.8 billion||$39.5 billion|
|Sanofi||$36.57 billion||$36.73 billion|
|GlaxoSmithKline||$34.79 billion||$29.84 billion|
|Gilead||$30.39 billion||$32.15 billion|
|AbbVie||$25.56 billion||$22.82 billion|
|Bayer||$25.27 billion||$24.09 billion|
Medical Device Manufacturers
Medical devices can be anything from hospital diagnostic equipment to hip and knee implants. Several companies only produce medical devices, but some drug manufacturers, such as Johnson & Johnson, also manufacture devices.
Like Big Pharma, medical device manufacturers also have a lobbying group to pursue their interests in Washington.Part of the total pharmaceutical industry lobbying price tag comes from the Medical Device Manufacturers Association (MDMA).
In 2016, it contributed $1.2 million in lobbying funds. Its efforts concentrate on medical device friendly bills in Congress mostly related to how companies pay taxes.
Five of the top medical devices companies have their headquarters in the U.S.: Johnson & Johnson, Baxter International, Abbott Laboratories, Stryker and Boston Scientific.
Top Medical Device Companies:
|Johnson & Johnson||New Brunswick, New Jersey||Hip and knee implants, surgical mesh, power morcellators|
|Siemens||Munich, Germany||Hearing aids, diabetes testing products, diagnostic machines|
|Medtronic||Dublin, Ireland||Cardiac devices, defibrillators, spinal implants, catheters|
|Roche||Basel, Switzerland||Diabetes testing products, cancer screening devices, research equipment|
|Baxter International||Deerfield, Illinois||Surgery products, dialysis machines, hospital devices|
|GE Healthcare||Little Chalfont, United Kingdom||Ultrasound machines, MRIs, CT scanners, ventilators|
|Abbott Laboratories||Chicago, Illinois||Catheters, stents, surgical guidewires|
|Phillips||Amsterdam, Netherlands||Ultrasound machines, CT scanners, mammogram machines, X-ray machines|
|Stryker||Kalamazoo, Michigan||Hip and knee implants, hospital beds|
|Boston Scientific||Marlborough, Massachusetts||IVC filters, surgical mesh|
Big Pharma’s Influence
Critics contend that Big Pharma uses manipulative tactics and expensive advertising to sway lawmakers, the FDA and the public to increase sales.
The public is exposed to Pharma’s misleading promotions and advertising. For example, critics say AbbVie and other companies who make testosterone replacement drugs such as AndroGel marketed their drugs as the fountain of youth to older men. They created a marketing campaign around the condition “Low T” that featured a quiz for men to self-diagnose Low T symptoms.
The testosterone market soared into the billions as a result. But few studies back up drug-company claims that the drug significantly enhances mood, vitality and sexual performance. Studies also link these drugs to heart problems. The FDA added a warning on the label after millions of men were already exposed to the risk.
The American public is not the only sector of society influenced by Big Pharma’s techniques. Doctors, scientists and research organizations, medical journals, teaching hospitals and university medical schools all exhibit disturbing conflicts of interest between their publicly stated missions and their financial and ideological subjection to Big Pharma.
Doctors conduct research with funds from Big Pharma. Private charities and foundations account for a mere 5 percent of the estimated $100 billion spent on biomedical research in the U.S. each year. Pharmaceutical and medical device companies contribute approximately 60 percent.
Big Pharma has a track record of hiring former government workers with valuable connections to gain political clout.
- 36 who worked for a member of Congress
- 13 who worked for a federal agency
- 12 who worked for a congressional committee
- Two who worked for the White House
- One who worked in the court system
Using these connections to pursue industry goals, Big Pharma has a significant competitive advantage over the public interest.
Marketing, Research and Development (R&D) and Drug Cost
Americans pay more than any other country in the world for pharmaceuticals — in some cases, thousands of dollars more per prescription. Big Pharma says this occurs because of the astronomical costs of developing a new drug.
The truth is that U.S. law allows drug companies to set the prices for drugs and protects them from free-market competition. Other countries set a limit on what companies can charge based on the benefit of the drug. The true cost of developing a drug is shrouded in mystery, with many unverifiable figures reported by Big Pharma.
Donald Light, a professor and expert on the pharma business model, said that while companies claim each new drug costs them $1.2 billion, the true cost is more like 60 million.
The industry also avoids talking about how much it spends on marketing, which is almost double what it spends on research.
Big Pharma Sways Opinions
The large amount of cash Big Pharma bestows on government representatives and regulatory bodies is small when compared with the billions it spends each year on direct-to-consumer advertising. The U.S. is one of only two countries in the world whose governments allow prescription drugs to be advertised on TV (the other is New Zealand).
In 2015, Big Pharma spent $5.4 billion on direct-to-consumer ads and fired off about 80 ads an hour, according to Nielsen.
Big Pharma also employs doctors, researchers and institutions.
The industry persuades doctors to allow ghostwriting, paying physicians to attach their names to positive articles about a particular drug with the goal of seeing it published in a reputable medical journal.
Often the commentary is little more than an advertisement penned by a company paid copywriter showcasing a new product. Big Pharma used ghostwriting to promote numerous drugs, including the antidepressant Paxil, the recalled weight loss drug Fen-Phen, the anti-epilepsy drug Neurontin, the antidepressant Zoloft and painkiller Vioxx, to name a few.
In addition, even when a medical reviewer writes a comprehensive assessment of a new drug for a medical journal, it is common practice for those supposedly unbiased professionals to be on Big Pharma’s payroll.
These slanted studies appear in medical journals that are widely hailed as collections of unbiased scientific evaluation and separated from the long financial arm of pharmaceutical industry influence. Yet Richard Smith, former editor of the British Medical Journal, says, “All journals are bought — or at least cleverly used — by the pharmaceutical industry.”
Big Pharma tends to weaken the objectivity of even the most honest health professionals while encouraging them to overprescribe medications. Consider the numbers:
- Advertising instead of research: For every $1 spent on “basic research,” Big Pharma spends $19 on promotions and advertising.
- Distribution of free drug samples: The U.S. has one pharmaceutical sales representative for every five office-based physicians.
- Sponsorship of symposiums and medical conventions: Drug and medical device makers spend lavishly on doctors, including covering meals, travel, seminars and conventions that sometimes look more like vacations.
Many medical journals, including the esteemed Journal of the American Medical Association (JAMA), actively vie for the attention of Big Pharma advertising dollars, billing themselves as the best way for drug companies to reach their professional readership.
How Big Pharma Influences Doctors and Researchers
Part of Big Pharma’s formula for creating blockbuster drugs is promoting to physicians and providing kickbacks and incentives to prescribe their expensive, brand name drugs.
Drug companies also buy doctors meals and pay them for “speaking engagements” in exchange for brand loyalty. One 2016 study in JAMA Internal Medicine found that when drug reps bought doctors just one meal costing less than $20 they were more likely to prescribe a promoted brand name drug.
According to ProPublica’s Dollars for Docs investigation, 1,866 companies paid $6.25 billion to doctors and hospitals from August 2013 to December 2015.
Drug and Device Company Payments to Doctors from Select Companies, August 2013 to December 2015:
|DePuy (Johnson & Johnson)||$167 million|
|Stryker Corporation||$153 million|
|Janssen Pharmaceuticals||$106 million|
|Boston Scientific||$77 million|
Big Pharma and Researchers
Then there are medical researchers, who are hardly immune to Big Pharma’s financial power. Because drug companies sponsor clinical trials that researchers are paid to administer, too often the academics and scientists are hired hands who supply human subjects and collect data according to the instructions of their corporate employers.
Sponsors keep the data, analyze it, write the papers and decide whether and when and where to submit them for publication. Drug companies also stage-manage trials to produce predetermined outcomes that will put their products in the best light.
Medical Schools and Big Pharma
Big Pharma has also infiltrated medical schools. Teachers, department chairs and deans often sit on drug companies’ boards of directors. This influences educational content. Money from Big Pharma supports programs within many medical schools and teaching hospitals, and company reps are given access to young doctors to promote their company’s drugs.
The result is that doctors not only receive biased information but also learn a drug-intensive style of medicine.
Sales reps may influence these doctors to believe that newer, more expensive drugs are always better than old ones.
In most states, doctors must also take accredited education courses, called continuing medical education (CME). The pharmaceutical industry provides a substantial proportion of the billions spent on CME annually and continues to use that support as a marketing tool.
In addition, academic centers are able to receive royalties from Big Pharma on any drug or technology they help to create and patent as a result of research — sometimes underwritten with government funds.
Columbia University, for example, received nearly $790 million from licensing agreements with biotech and pharmaceutical companies during the 17-year life of its medical school’s patent on a method for synthesizing certain biological products.
Big Pharma Fraud Settlements
In a 24-year period, Big Pharma companies paid 373 settlements totaling $35.7 billion for marketing fraud, according to Public Citizen’s 2013 report Pharmaceutical Industry Settlements: 1991 through 2015.
The most common charge involved drug-pricing scams against state Medicaid programs. This meant state taxpayers ended up footing the bill while Big Pharma made billions.
Unlawful promotion of drugs yielded the biggest settlements. But these investigations take many years to complete. By then, drug companies have made hundreds of millions or even several billion, while the U.S. Department of Justice fine is typically only a few million.
This makes it too profitable to stop breaking the law for many companies, according to Michael Bobelian of Forbes Magazine.
Several of the biggest drug and medical device companies sell the majority of their products in the U.S. Many of these products are involved in product liability litigation. Some of the companies’ best-selling drugs brought in over a billion in 2016, according to company annual reports.
AbbVie Inc. is a pharmaceutical company that spun off from Abbott Laboratories in 2013 and markets dozens of products. The Illinois-based group generates most of its revenue from Humira, an anti-inflammatory drug used to treat arthritis, and from AndroGel, a testosterone replacement therapy (TRT) gel that treats low testosterone (“Low T”) in men. Humira was the world’s No. 1 drug in 2016, bringing in $16.7 billion.
- Business: Develops and markets more than 45 drugs in the U.S.
- Products Involved in Current or Past Litigation Include:Nexium (acid reflux), Onglyza (Type 2 diabetes), Crestor (cholesterol), Farxiga (Type 2 diabetes), Seroquel (antidepressant)
- Top Selling Drugs 2016: Crestor, Symbicort (asthma, COPD), Nexium
AstraZeneca is a U.K.-based biopharmaceutical company that develops and markets drugs in areas ranging from cardiovascular and metabolic diseases to oncology. The company grew from the merger of Astra AB and Zeneca Group PLC in 1999. The company bought partner Bristol-Myers Squibb’s diabetes division in 2014.
The Bayer Group is a leading global innovator with 280 subsidiaries worldwide in the fields of health care, agriculture, synthetic materials and business services. In 2016, it signed a deal for a $66 billion merger with agriculture giant Monsanto. Bayer is known for its focus on birth control, and its products include birth control pills Yaz and Yasmin, its Mirena IUD and Essure permanent birth control. All of these products led to litigation.
- Business: Sells and markets more than 35 drugs in U.S.
- Products Involved in Current or Past Litigation Include: Pradaxa (blood thinner), Tradjenta (Type 2 diabetes)
- Top Selling Drugs 2016: Spiriva (asthma), Pradaxa, Trajenta
Boehringer Ingelheim, the world’s largest family owned pharmaceutical company, develops and manufactures drugs for a wide range of medical conditions, including cancer, diabetes and hypertension. In addition, Boehringer produces drugs and biologicals veterinarians use for animal health. Albert Boehringer founded the company in 1885, and its success continues to this day. Headquartered in Ingelheim, Germany, the drugmaker employs more than 47,000 people who operate its 145 branches worldwide.
- Business: Manufactures medical devices for several health needs, including cardiovascular, digestive and gynecological diseases.
- Products Involved in Current or Past Litigation Include: Various transvaginal mesh brands
- Top Selling Devices 2016: Defibrillators and single-use medical devices
Boston Scientific is a worldwide manufacturer of medical devices that researches, develops and sells an expansive line of products and technologies used to diagnose and treat medical conditions. The company provides solutions for neurological conditions, cardiovascular disorders, urological and gynecological disorders and diseases of the digestive system, airways and lungs. It operates 12 manufacturing facilities across the globe.
The company officially became Bristol-Myers Squibb (BMS) in 1989. It is known for innovation in biological and pharmaceutical research, including the antipsychotic Abilify (which it co-markets with Otsuka America Pharmaceutical, Inc.) and its blood thinners, Plavix and Eliquis. When Bristol-Myers Squibb acquired Amylin in August 2012, it gained control of its blockbuster diabetes medications, Byetta and Bydureon.
- Business: Manufactures cardiovascular, urological and surgical products, including surgical mesh
- Products Involved in Current or Past Litigation Include: Kugel Hernia Mesh Patch, IVC Filters (Recovery, G2, G2 Express), transvaginal mesh
- Top Selling Devices 2016: Biopsy devices, IVC filters, catheters
Charles Russell Bard began a medical company in 1907 to help treat urinary discomfort. Today the business, known as C.R. Bard, sells 8,000 products in the fields of oncology, urology and surgery. The company operates and sells its products in 80 countries. It faces litigation related to its transvaginal and hernia mesh products as well as its IVC filters.
- Business: Sells and markets a number of health products including catheters and transvaginal mesh.
- Products Involved in Current or Past Litigation Include: Transvaginal mesh
- Top Selling Devices 2016: Ostomy products, catheters, surgical mesh
Coloplast is a Denmark-based company that supplies “intimate health care products” — including catheters, ostomy bags, wound dressings, skin cleansers, antifungal products and vaginal mesh — to hospitals and retailers and directly to consumers in some markets. The headquarters is in Humlebaek, Denmark, and the U.S. headquarters is in Minneapolis.
- Business: Manufactures medical devices in a number of areas from oncology to women’s health.
- Products Involved in Current or Past Litigation Include: Biodesign and Surgisis transvaginal mesh, Celect IVC filter, Gunther Tulip IVC filter
- Top Selling Devices 2016: Hospital surgical equipment, IVC filters
Cook Medical, a division of Cook Group Incorporated, is a global manufacturer of minimally invasive medical devices. The company offers approximately 16,000 products for a wide range of clinical specialties ranging from surgery to oncology and women’s health. Established in 1963, Cook Medical employs nearly 2,500 employees.
- Business: Sells and markets 8 drugs in the U.S.
- Products Involved in Current or Past Litigation Include: Benicar (blood pressure)
- Top Selling Drugs 2016: Benicar (blood pressure), Azor (blood pressure), Tribenzor (blood pressure)
Daiichi Sankyo is a global pharmaceutical holding company and the second-largest drug company in Japan. It makes pharmaceuticals for people and animals and manufactures medical tools and equipment. It also produces food, food additives, livestock feeds and agrochemicals. Its top-selling blood pressure drug, Benicar (olmesartan medoxomil), brought in $3.1 billion worldwide in 2013 and $2.4 billion in 2014, making up more than a quarter of the group’s sales.
- Business: Sells and markets more than 40 drugs in the U.S.
- Products Involved in Current or Past Litigation Include: Cymbalta (antidepressant), Prozac (antidepressant), Actos marketed with Takeda (Type 2 diabetes), Zyprexa (antipsychotic)
- Top Selling Drugs 2016: Cialis (erectile dysfunction), Alimta (chemotherapy), Forteo (osteoporosis)
Eli Lilly & Co. is an international pharmaceutical manufacturer based in Indianapolis. Launched in 1876 by cotton-farmer-turned-pharmacist Colonel Eli Lilly, the company markets its products in 125 countries and has manufacturing plants in 13 countries. The company specializes in the areas of diabetes, bio-medicines, emerging markets, oncology and animal health. It is known for such advancements as selling the first commercially available insulin and being among the first to mass-produce penicillin.
- Business: Sells and markets about 60 drugs and medical devices in the U.S.
- Products Involved in Current or Past Litigation Include: Percocet (painkiller), Fortesta (testosterone replacement), Aveed (testosterone replacement), transvaginal mesh products
- Top Selling Products 2016: Fortesta, Aveed, Xiaflex (treats Dupuytren’s contracture – thickening of tissue in skin or hand)
Endo International is a small, specialty health care company with a global headquarters in Dublin, Ireland, and a U.S. headquarters in Malvern, Pennsylvania. The company employs several thousand employees worldwide. Endo develops, manufactures, markets and distributes pharmaceutical products and medical devices through its four operating companies: American Medical Systems (AMS), Endo Pharmaceuticals, Paladin Labs and Qualitest.
GlaxoSmithKline (GSK) is one of the world’s largest pharmaceutical companies. Based in Brentford, England, GSK was built through mergers of smaller companies that existed as early as the 1800s. It employs more than 97,000 people in three departments: pharmaceuticals, vaccines and consumer health care. GSK has faced tens of thousands of personal injury lawsuits for Avandia as well as federal fraud charges resulting in a $3 billion fine.
Johnson & Johnson
- Business: Sells and markets more than 180 drugs in the U.S. and hundreds of medical devices such as hip, knee, breast and transvaginal mesh implants.
- Products Involved in Current or Past Litigation Include: DePuy ASR Hip Implant, Pinnacle Hip Implant, Ethicon Gynecare Prolift mesh implant, Gynecare TVT mesh implant, Physiomesh hernia mesh, Ethicon power morcellators, Risperdal (antipsychotic), Invokana (Type 2 diabetes), Xarelto (blood thinner)
- Top Selling Drugs & Devices 2016: Xarelto, Invokana, Remicade (rheumatoid arthritis, Crohn’s), Invega (antipsychotic)
Johnson & Johnson (J&J) is a pharmaceutical company that engenders trust by offering a variety of inexpensive but useful medical products like Band-Aids, Tylenol and Baby Shampoo. J&J has around 250 subsidiaries and is the largest health care company in the world. It manufactures medical devices through subsidiaries Ethicon and DePuy and prescription drugs through Janssen Pharmaceuticals.
Merck & Co.
- Business: Sells and markets more than 119 drugs in the U.S.
- Products Involved in Current or Past Litigation Include: Vioxx (painkiller), Fosamax (prevents bone loss), Januvia (Type 2 diabetes), NuvaRing (birth control), Propecia (male hair loss)
- Top Selling Drugs 2016: Januvia, Gardasil (HPV vaccine), Zetia (cholesterol)
Merck & Co., the second-largest U.S. drug company, is a force to be reckoned with. Its parent company opened in Germany in 1668, and the U.S. company was established in 1891. Merck & Co. sells a vast array of products, including Claritin, Dr. Scholl’s products, vaccines, antibiotics, blood pressure drugs, heart drugs and Vioxx, a painkiller. Vioxx brought scandal to the company, as thousands of users reported instances of cardiac side effects, some fatal outcomes. Tens of thousands of lawsuits targeted Merck. The company paid out billions of dollars in settlements.
- Business: Sells and markets more than 330 drugs in the U.S.
- Products Involved in Current or Past Litigation Include: Lipitor (cholesterol), Eliquis (blood thinner), Zoloft (antidepressant), Effexor (antidepressant), Bextra (painkiller), Viagra (erectile dysfunction)
- Top Selling Drugs 2016: Lyrica (epilepsy and fibromyalgia), Eliquis, Viagra
Operating in more than 150 different countries and employing more than 110,600 people around the world, Pfizer is one of the world’s largest pharmaceutical companies and manufactures products in five areas: specialty care and oncology, animal health, primary care, nutrition and consumer health care. In 2009, Pfizer faced both criminal and civil allegations over illegal marketing of drugs like Bextra, Geodon, Zyvox, Lyrica, Neurontin, Detrol and Lipitor. Pfizer agreed to a $2.3 billion settlement and a five-year integrity agreement with the U.S. Department of Health and Human Services.
- Business: Manufactures several medical devices, including hip and knee implants.
- Products Involved in Current or Past Litigation Include: Rejuvenate and ABG II hips implants, TMZF femoral stems (including the Accolade, Citation and Meridian implants), LFIT cobalt-chromium V40 femoral head
- Top Selling Devices 2016: Endoscopy, surgical instruments and knee implants
Stryker Orthopaedics, which controls about 25 percent of the U.S. hip and knee implant market, started as a small business with a single product: a mobile hospital bed. The orthopedic division is one part of Stryker Corp. Two of Stryker’s hip designs, the Rejuvenate and ABG II, come with metal parts linked to corrosion and metal poisoning. An estimated 20,000 Americans received one of these devices before they were recalled in 2012.
- Business: Manufactures several drugs for sale in the U.S.
- Products Involved in Current or Past Litigation Include: Actos (Type 2 diabetes)
- Top Selling Drugs 2016: Various oncology drugs
Takeda, which began as an herbal medicine shop in 1781, has rapidly expanded since the late 1990s. The company now operates in than 70 countries worldwide. Takeda’s core business is based on drugs that treat gastrointestinal disorders, central nervous system (CNS) conditions, cardiovascular or metabolic conditions and cancer.